How Can Theory of Constraints Help in Software Optimization?

"Programmers waste enormous amounts of time thinking about, or worrying about, the speed of noncritical parts of their programs, and these attempts at efficiency actually have a strong negative impact when debugging and maintenance are considered. We should forget about small efficiencies, say about 97 percent of the time: premature optimization is the root of all evil."        —Donald Knuth (adapted from C. A. R. Hoare)

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